In a ground-breaking medical achievement for coastal Karnataka, doctors at Indiana Hospital & Heart Institute have successfully implanted the region’s first-ever artificial intelligence (AI)-driven, leadless pacemaker in an elderly woman. This milestone marks a significant advancement in cardiology and reinforces Mangaluru’s reputation as a hub for cutting-edge healthcare services.
The patient, who had been suffering from Tachybrady syndrome, a condition where the heart alternates between dangerously fast and slow rhythms, had been hospitalized multiple times over the past year due to heart failure. After extensive evaluation, doctors recommended a radiofrequency ablation and pacemaker implantation.
However, a traditional pacemaker was not a viable option due to the patient’s pre-existing infection and high risk of recurrent sepsis. Conventional pacemakers use leads connected to the heart and positioned on the chest wall, which can pose serious infection risks for vulnerable patients.
To overcome these challenges, a team of experts, led by Dr Yusuf Kumble, chief interventional cardiologist at Indiana Hospital, along with Dr Maneesh Rai (Electrophysiologist), Dr Garry Valerian Pais (Consultant Interventional Cardiologist), Dr Sukhen Shetty (Cardiac Anaesthetist), and Dr Pradeep, opted for an innovative, leadless pacemaker solution.
Unlike traditional devices, this self-contained pacemaker is implanted directly into the heart through a minimally invasive procedure via the groin, eliminating the need for external leads or chest wall placement. This significantly reduces infection risks and complications, making it a safer, more effective option for patients prone to infections. Following the successful implantation, the team also performed radiofrequency ablation to treat the patient’s arrhythmias.
“This achievement underscores the exceptional expertise of our cardiology team and our commitment to bringing cutting-edge medical technologies to Mangaluru and beyond,” said Dr Yusuf Kumble. “By implanting the first AI-driven wireless pacemaker in coastal Karnataka, we have further established Indiana Hospital as a leader in interventional cardiology, not just in Karnataka, but across India.”
The leadless pacemaker is smaller, more efficient, and less invasive than conventional devices, providing patients with enhanced quality of life while minimizing associated risks.
With this pioneering procedure, Indiana Hospital and Heart Institute continues to set new benchmarks in advanced cardiac care, further cementing Mangaluru’s position as a center for innovative medical interventions in India.
source: http://www.daijiworld.com / Daijiworld.com / Home> Top Stories / by Media Release / February 18th, 2025
Dr. Fatima Jalid, an Assistant Professor in the Department of Chemical Engineering at the National Institute of Technology (NIT) Srinagar, has been recognized in the newly published book She Is – 75 Women in Chemistry.
Published by Beyond Black in collaboration with the Office of the Principal Scientific Adviser (PSA) to the Government of India and the Royal Society of Chemistry (RSC), UK, the book was unveiled on February 6 at the Indian Institute of Science Education and Research (IISER) in Bhopal. It is the fourth edition in the She Is series and highlights the achievements of 75 Indian women making remarkable contributions in chemistry and related fields.
The book, authored by Elsa Marie D’Silva and Supreet K Singh, sheds light on the journeys of women from Tier 2 and Tier 3 cities who have persevered against challenges to establish themselves in the field of chemistry. The authors emphasize that these women serve as beacons of inspiration, proving that determination and dedication can lead to excellence in scientific research.
Dr. Jalid’s research at NIT Srinagar focuses on developing chemical compounds and processes with applications in material science, environmental chemistry, and biotechnology. By integrating interdisciplinary approaches, she has advanced scientific knowledge in both theoretical and applied chemistry.
In a male-dominated field, Dr. Jalid has emerged as a role model for aspiring women in STEM. Her mentorship has created an inclusive academic environment at NIT Srinagar, encouraging more female students to pursue careers in scientific research. Actively involved in initiatives promoting women in science, she has organized workshops, seminars, and outreach programs to enhance female representation in STEM fields.
Believing that science should be accessible to all, Dr. Jalid advocates for inclusivity in research, ensuring that knowledge benefits society beyond socio-economic and gender barriers. Her published research papers in reputed international journals have received significant citations, further cementing her impact in the field.
The book She Is – 75 Women in Chemistry is available online for purchase at ₹1,645.
source: http://www.radiancenews.com / Radiance News / Home> Focus> Markers of Excellence / by Radiance News Bureau / February 16th, 2025
After three years of relentless efforts, mathematics teacher Bilal Ahmad Mir is set to launch his solar-powered car, RAY, revolutionizing eco-friendly transportation. The much-anticipated vehicle will hit the roads on Monday, February 10, marking a significant step in clean energy innovation.
Mir, who entirely self-funded his project with an investment of ₹20-22 lakh, embarked on this journey in 2022. He extensively studied automobile designs from the 1950s to modern-day luxury cars, incorporating cutting-edge technological advancements into his solar vehicle. His research, published in six countries, has earned him the moniker ‘Elon Musk of Kashmir’.
The RAY solar car boasts a 1 kW solar-powered engine, a high-tech Battery Management System (BMS), and autonomous parking sensors. Its gull-wing doors, embedded with solar panels, enhance both aesthetics and energy efficiency. Unlike traditional electric cars that require sunlight for charging, RAY can charge itself even in cloudy or snowy conditions.
Mir initially caught the attention of Mahindra Group Chairman Anand Mahindra, but a potential collaboration fell through due to technical constraints. Despite this, Mir remains optimistic about his prospects in the global market.
While Indian manufacturers are producing electric vehicles, Mir believes his solar innovation faces no domestic competition. Instead, he aims to compete with international firms like Lightyear and Aptera Motors, both pioneers in solar-powered vehicles. His research continues to receive global recognition, further strengthening his reputation in the field.
The prototype of RAY was developed by modifying a 1988 Nissan Micra, a process that took Mir 13 years of dedication. The car, which features a dual power system—solar energy and a rechargeable battery—will officially launch on February 10 and is expected to hit the roads by June 2025. However, Mir remains tight-lipped about future production plans.
As the world shifts toward sustainable solutions, Bilal Mir’s innovative solar car serves as an inspiration for India’s clean-energy future.
source: http://www.radiancenews.com / Radiance News / Home> Pride of the Nation / by Radiance News Bureau / February 11th, 2025
He can afford to hand out fistfuls of Liv.52 to anyone feeling liverish, although he would prefer to sell the pill. As Meraj Manal says, one Liv.52 is bought every second somewhere in the world. The only ayurveda pill among the 12 bestselling medications in India, Liv.52 has powered its manufacturer The Himalaya Drug Co into the ranks of Big Pharma in India.
But ask Manal to sell a slice of his privately-held company and you are shown the door. Many consumer care companies have tried to acquire a stake in Bangalore-based Himalaya. Dealmakers know it is not up for sale, but they do not give up hope or stop making bids.
Why should they? Himalaya, started by Manal’s father, the late M. Manal, in 1930 to make herbal tablets in the Himalayan town of Dehradun, is today an established brand in over 70 countries with about 160 products – 66 in pharma, 63 in personal care, nine in baby care and 22 in animal care.
After India, its three top markets are West Asia, Russia and the CIS, and South East Asia. In 1999, Himalaya took its personal care range into global markets, piggybacking the equity of its pharma products.
Figures are not available, but Manal says turnover has crossed Rs 1,000 crore on the back of Liv.52, some similar pills and the personal care products. “Liv.52 is one of the biggest successes of my father,” says Manal, Chairman of Himalaya Global Holdings, which owns the nine operating subsidiaries in different regions.
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I get 3 or 4 offers a year: Meraj Manal
Meraj Manal, 62, has always let his business heads to do the talking. In a rare interview with BT’s K.R. Balasubramanyam, he explains why he does not want outside investments, and why values count more than profits. Edited excerpts
How did your father get into the herbal medicine business? My father spent his lifetime gathering knowledge about traditional household remedies, standardising them, testing them for safety and efficacy and demonstrating them to doctors. He was the first who thought of producing herbal medicines in tablet form so doctors can prescribe them… Whenever he heard about a remedy, he would jot it down on a plain card to work on them later. We have tens of thousands of such cards stored in boxes. Our toothpaste is a product from one such card scribbled 40 years ago.
Why are you still not a public company? I don’t want a rupee from anyone other than the bank, because it is difficult to explain what we do to a shareholder. Can I accept outside investments and allow these cards (pointing to the stacks of his father’s cards) to disappear? Our whole philosophy, our value system is so different, how do I explain this to investors? All my children – four daughters and three sons – think so.
Do you get offers? I receive three or four offers a year. Multinationals have spoken to me and one of them even said we are the nugget of the herbal industry. If I accept these offers and put that money in a bank, I would no doubt get millions every month… What will I do with that money? I don’t want the liability of someone else’s money with me, big or small. Once you accept outside investment, they will start advising us on things like cutting the number of curries in the lunch at our canteen… or the staff transport. They will ask us why you are doing this and that. There is no “why” here. This is how it is. Since we are closely held, I have the luxury to say profits are not everything.
How much of your revenues goes into R&D? In this company, there is no limit on expenses on R&D. That is the only division without a budget. These (pointing to the cards) have to be converted into products.
How are you professionalising the company? As you grow, you need people who know more than you do. You cannot reach the next step unless you professionalise…. We will reserve the holding company for family members and the subsidiaries will have only professionals. We have separated ownership from management. Family members will be responsible for nurturing our value system. I don’t want family members on the business side. If they have energy, they are free to go out and pursue their interests.
So a family member becomes part of the holding company by default? Admission is not by default. They must have something to contribute….My son heads the US business, and not because he is my son, but because he is a professional who knows the US market the best. He is doing remarkably well.
What about this Deputy Chairman’s post? I created the post two years ago and appointed Ravi Prasad for a very special reason. To send a strong message that the operational head does not have to be a Manal. People were astonished and are happy about the decision. Like any CEO of any other region, my son too reports to Ravi. (Ravi Prasad was elevated as Executive Chairman in October. He leads the global management team.)
Are you satisfied with your growth? The growth we have had is more than satisfactory. If I want more than that, then we are greedy. We crossed Rs 1,000 crore in revenues last year. I don’t know much about finances. Professionals handle that. I just sign on the papers. …When I joined the business in 1965, the revenues were Rs 40 lakh…. The way we are growing in North and South America tells me that 20 years from now, they could possibly be our largest markets by volume.
Where is Himalaya headed? We will never move from our core competence. I am not for diversifying. I am not a person who can do other things. Opportunities for growth are unlimited and there is no real need to diversify. Our global operations have taught us many things. The country does not matter. As long as there are homes with people, we will go there.
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Research backbone Although Himalaya’s reliance on Liv.52 has come down after both its new as well as old pharma products picked up steam in the market, and it launched personal care products, it all began with this blockbuster, whose recipe was among the many jotted down by Manal’s father on a card.
(Himalaya’s future lies in thousands of similar cards with notes that are stacked in boxes in Manal’s room.) The 52nd formula was a hit. Manal senior’s aim had been to make herbal remedies available in tablet form, scientifically tested for efficacy, identified by name and prescribed by doctors. The passion for research continues.
Ravi Prasad
Himalaya has raised its research, development and manufacturing standards so that its products clear regulatory hurdles abroad. “Apart from ayurvedic institutions, we also do clinical trials in leading allopathic institutions both in India and abroad,” says Ravi Prasad, Executive Chairman of Himalaya Drug Company, who leads the team of professionals worldwide.
“The regulatory picture is not clear in many countries and in some countries our standards have been recognised as the benchmark,” he says. Himalaya’s R&D facility, he says, is one of the biggest for an ayurveda manufacturer, with about 120 multidisciplinary scientists. As Manal proudly declares, R&D is the “backbone” of the company.
Himalaya knows the key to growth lies in its ability to create more patents. The US Patent and Trademark Office has granted it patents for its sunscreen, under-eye cream, laxative, sedative, immunestimulant, anti-acne range and hairloss cream, and 76 applications are pending. It has just released in the US markets a new type of tablet in which the binders are also derived from herbs. “No company has done this before, and we have filed for a process patent,” says Ravi Prasad. Until the 1990s, Himalaya’s portfolio had only pharma remedies. It entered the equally lucrative consumer care market with some 20 products under the Ayurvedic Concepts range in 2001. Two years later, it created the umbrella brand Himalaya Herbal Healthcare. It also began opening exclusive outlets: there are 130 shops in India and 25 in Singapore, Malaysia, South Africa and the Cayman Islands.
Dream run According to Ravi Prasad, Himalaya’s personal care products are growing much faster globally than pharma products, because pharma faces tough regulations in some countries. As of now, Himalaya gets 58 per cent of its revenues from pharma products, but that seems set to change. Saket Gore, Business Head of the consumer products division, says: “Today, we are the market leaders in face washes in the UAE, India and Malaysia.”
According to The Nielsen Co figures for April-June 2010, Himalaya face washes had a 17.8 per cent market share in India, less than two percentage points behind multinationals Hindustan Unilever Ltd and L’Oreal. Himalaya’s individual products also face competition from firms that are strong in one or just a few products, such as Colgate in toothpaste and Fair & Lovely in face masks. Doctors have been Himalaya’s biggest brand ambassadors in pharmaceuticals.
Philipe Haydon, President & CEO for pharmaceuticals, says Himalaya is in touch with about 3.75 lakh doctors and reaches 94 per cent of pharma retailers. “We are the modern face of ayurveda in India and our medical representatives promote products with scientific detailing,” says Haydon, who is also the CEO of the Asia Pacific region. In ayurveda retail, Himalaya competes with the likes of Dabur, Charak, and Baidyanath
Source: Indian Pharmaceutical Market rankings based on Org SSA report / Aug 2010
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Internationally, consumer care and pharma contribute equally to revenues. “In 20 years from now, North and South America could possibly be our largest markets by volume. They are very big on herbal medicine,” says Manal. These markets are headed by his son Nabeel, 36.
The Prognosis Industry observers believe that while Himalaya has built a cult in Liv.52, it needs more such blockbusters to make up for its low-key marketing and a distribution network weaker than that of rivals such as Dabur India.
“Today, the brand Himalaya is recognised and closely associated as a natural remedy, but on the personal-care front it sends out no cues to a consumer. This is important in the FMCG category where it competes with many others,” observes Kannan Sitaram, a former chief operating officer of Dabur.
Analysts say that opening shop-in-shops and branded stores is a good strategy. “But brandbuilding investments are required so that consumers will walk into a shop only for the Himalaya display. Also, being positioned as a mass brand, it needs greater presence and investment in distribution,” says Sitaram. But the company has to figure out if its returns are justified. “After all, rentals are going up,” he says.
In pharma, Himalaya is stronger. “It has very sharply- positioned products for the eyes, liver, bones and so on. It is also present in areas that are not crowded. Besides, it spends huge sums on R&D and can compete with some of the best pharma companies in India,” says R.B. Smarta, Managing Director, Interlink Marketing Consultancy.
This also gives it an edge in global markets, where the demand for natural, ayurvedic and herbal remedies is growing. “They have very precise and extensive documentation on each of their ingredients, that can withstand the rigor of clinical trials. Their patents also stand them in good stead,” says Smarta.
By buying raw materials directly from growers, collectors and nongovernmental organisations, Himalaya keeps costs under control. Recently, it signed an agreement with the Sikkim government to prepare farmers in organic farming of herbs and sustainable collection. In September, Himalaya, along with a few others, came under fire from the Centre for Science and Environment or CSE, which claimed that Himalaya’s honey contained antibiotics beyond the stipulated standards. Ravi Prasad denies the charge. “The same batch was tested at three independent laboratories and none found any trace of antibiotics.
Our technical team will soon meet the CSE with these findings and seek its comments,” he says.
No entry Manal does not run day-to-day affairs and has professionalised the company by elevating Ravi Prasad as the executive head, so that his father’s legacy grows independent of the family. “My father’s life’s mission was to help people and we will move in his footsteps,” says Manal, who follows the modest example set by his father. (In September, when Ravi Prasad called on Manal at his apartment in Dubai, the chairman travelled with him to Himalaya’s office in the Metro and then took a bus to attend another meeting.)
Of Manal’s seven children, only Nabeel works for the company. Two daughters are married and homemakers, and the other two daughters and a son are still studying. One son works in the financial sector in the US. Manal is content with bank funding, and proud of his 40-yearold relationship with Union Bank of India. In turn, M.V. Nair, the bank’s Chairman and Managing Director, says its long relationship with Himalaya is a wonderful example of a banker- entrepreneur growth story.
Himayala’s requirement of funds depends on projects. It borrowed Rs 100 crore two years ago from the bank to make its manufacturing unit in Bangalore compliant with European and American standards.
Dealmakers and investment bankers are not put off by Manal’s “No Entry” board. Recently a personal-care multinational contacted Bangalore’s Viedea Capital Advisors, looking for a sizeable stake in Himalaya. Deepak Srinath, cofounder of Viedea, says: “The management did not entertain any conversation on the subject.”
Himalaya, Srinath says, is a dream mandate for any investment banker because it has all the ingredients that a PE or strategic investor looks for – a highly credible brand name, an impressive product portfolio, a professional management and profitability.
“Also, the promoters have a reputation for being ethical,” says Srinath. According to the India head of an American PE firm, Himalaya is an ideal target since its capex needs are not large and can be met by internal accruals and bank funding. Such companies usually give robust returns.
But Manal is focused on different things: “The scope for growth is unlimited. As long as there are homes with people, that family is our customer. We don’t recognise borders.”
With inputs by Shamni Pande
source: http://www.businesstoday.in / Business Today.in / Home> News> BT Magazine> Features / by K R Balasubramanyam / Print edition / November 28th, 2010
From technology to hospitality, Muslim businessmen are raising India’s stature on the global stage
New Delhi :
In the ever-evolving world of business, several prominent figures are not just shaping the Indian economy but also placing the country on the global map. Among them, six Muslim businessmen stand out, with their remarkable ventures spanning across various sectors, such as technology, healthcare, retail, and hospitality. These influential entrepreneurs are enhancing India’s image worldwide, further solidifying its position in the global business arena.
Azim Premji – The Tech Magnate Azim Premji, often regarded as the richest Muslim businessman in India, has played a pivotal role in the growth of India’s technology sector. As the chairman of Wipro, one of the country’s largest IT companies, Premji’s leadership has helped the company expand its reach across various international markets. His contributions extend beyond the business world as well. “India’s rise in the global tech landscape is closely tied to Wipro’s innovation and excellence,” said Premji. Through Wipro, Premji has established himself as a philanthropist, with substantial donations to charitable causes.
Meraj Manal – The Herbal Business Visionary Meraj Manal, the driving force behind the success of ‘Himalaya,’ India’s prominent herbal company, is known for his dedication to promoting natural wellness. His business expertise has helped Himalaya expand into a globally recognised brand, selling products in over 90 countries. Manal attributes his success to innovation and a commitment to quality. “We’re not just selling products; we’re selling a way of life,” he shared. His continued success has played an essential role in reinforcing the global appeal of Indian herbal and natural products.
Rafiq Malik – Footwear Industry Leader Rafiq Malik, founder and owner of ‘Metro,’ one of India’s leading footwear brands, has seen significant international growth. His entrepreneurial vision has positioned Metro as a key player in the retail space, both in India and abroad. Under his leadership, Metro has expanded its footprint, contributing to the growing demand for Indian brands in global markets. “Metro is about more than just shoes; it’s about delivering quality and style to every customer,” said Malik.
Yusuf Ali – Hospitality and Retail Mogul Yusuf Ali, owner of ‘Lulu,’ one of the largest retail chains and shopping malls in many world countries and in India, has firmly placed his mark in the retail and hospitality sectors. With Lulu Mall’s presence in multiple countries, his business is recognised globally. From large-scale shopping centres to luxury hotels, Yusuf Ali’s diverse portfolio is a testament to his entrepreneurial prowess. “Our mission is to provide an unparalleled shopping experience for our customers, no matter where they are,” Yusuf Ali explained.
Other Notable Names While Premji, Manal, Malik, and Yusuf Ali are among the most prominent, several other Muslim businessmen are also contributing significantly to India’s economic growth. Their ventures span multiple industries, from healthcare to infrastructure, highlighting the diversity and dynamism of Muslim entrepreneurs in India.
These businessmen not only continue to lead successful ventures but also serve as role models for the younger generation, proving that entrepreneurship knows no bounds. Through their business acumen, these individuals are ensuring that India continues to grow as an economic powerhouse on the global stage.
source: http://www.clarionindia.net / Clarion India / Home> Editors Pick> India / by Team Clarion / December 07th, 2025
In an era where medical expenses are skyrocketing, a doctor from Patna has been a beacon of hope for the poor and underprivileged.
For an astonishing three decades, Dr. Ejaz Ali has been charging a mere Rs 10 for consultation, earning him the revered title of “messiah” among his patients.
From March 20, 2008, to July 7, 2010, he represented the Janata Dal (United) in the Rajya Sabha from Bihar. He has also served as the National Convenor of the All-India Backward Muslim Morcha, an organization dedicated to campaigning for Dalit Muslims since its founding in 1994.
Since 1984, Dr. Ali has worked as a general surgeon in Bikhna Pahari, Patna. The kind physician took a different approach, while the others around him charged exorbitant fees. By keeping his fees at Rs 10, he made himself available to those in need.
His clinic, which is situated in Bikhna Pahari on Ashiana-Digha Road, draws patients from all across Bihar who are looking for reasonably priced healthcare.
With more than 100 patients every day and multiple surgeries completed, Dr. Ali’s dedication to affordable healthcare is clear. He emphasizes his consistent commitment to aiding people in need. In order to save them money on lodging and other costs, he makes sure that every patient who has travelled to visit him receives a consultation that same day.
In addition to charging minimal fees for consultations, Dr. Ali performs surgeries at a reasonable cost. He permits his patients to pay in installments and even declines to charge them.
The late wife of Dr. Ali was a doctor as well. His three children now work in the same field, truly carrying on their father’s legacy. They asserted that their father has always put patients first.
His daughter, Gynecologist Dr. Suraiya Anjum, says, “He is the type of person who never yells or becomes agitated. Patients frequently regard him like a messiah.
Despite his fame and recognition, Dr. Ali remains humble and dedicated to his work. His clinic continues to attract patients from all over the state.
source: http://www.twocircles.net / Two Circles.net / Home> Articles> Indian Muslim / by TCN News / February 03rd, 2025
The valedictory function of the 4th Asian Congress for Alternatives to Animal Experiments held at Jamia Hamdard Convention Centre where Prof. (Dr.) M. Afshar Alam, Vice-Chancellor, Jamia Hamdard was the Chief Guest of the programme.
Organizing secretary Prof. S. Raisuddin informed that this congress is being held for the first time in India. During this congress the founding members of the society and representatives from India, China, Japan, and South Korea signed a joint declaration to establish the Asian Federation of Societies for Alternatives to Animal Experiments (AFSAAE).
Well-wishers from societies working for alternatives from America, Europe, and Sri Lanka also wished good link to the foundation. All the representatives were felicitated by the Organizing Secretary. Prof. Y.K. Gupta and Dr. M. A. Akbarsha graced the occasion as Guest of Honour.
Prof. Y. K. Gupta urged the scientists to understand the pain of Animals while using them for scientific experiments.
Dr. Akbarsha announced the next meeting to be held at Hyderabad. Prof. Raisuddin presented a detailed report of 3 days deliberations during the conference. He also announced various awards for best presentations by young scientists. Dr. Christian Pellevoisin, Scientific Director, MatTek & CEO Urbilateria France sponsored best poster presentation awards and cash prizes to the budding scientists. Dr. Kristie Sullivan, Vice President, Education and Outreach, Institute for In Vitro Sciences, USA and Prof Winfried Neuhaus, member of the Austrian Commission for Animal Experimentation also appreciated the successful organization of the Congress.
Prof. (Dr.) M. Afshar Alam, Vice Chancellor congratulated the Organising committee members for the successful organisation of the conference. He appreciated the patronage of Janab Hammad Ahmed, Chancellor, Jamia Hamdard and financial support of Hamdard National Foundation along with other funding agencies for enabling Jamia Hamdard to develop alternative models of animal experiments.
Programme ended with vote of thanks by the Organising Secretary and National Anthem.
source: http://www.taasir.com / Taasir.com / Home> Education / by Taasir News Network / December 15th, 2024
In a landmark achievement, the Government of India has recently awarded Patent No. 556810 to Jamia Millia Islamia (JMI) scholars Dr. Tanveer Ahmad, an Assistant Professor, and his PhD student, Miss Nisha Chaudhary, from the Multidisciplinary Centre for Advanced Research & Studies (MCARS) at JMI.
The patent granted on December 24, 2024, recognises their pioneering invention titled “A SYSTEM AND METHOD FOR GENOMIC MARKERS AND DIGITAL PATHOLOGY IMAGE-BASED PREDICTION OF ORAL MALIGNANT DISORDERS.”
Their innovative methodology, developed in collaboration with partners, leverages artificial intelligence (AI) and digital pathology to enhance the diagnosis and prediction of oral cancer.
Miss Nisha Chaudhary and Dr. Tanveer Ahmed
This advanced system can study tissue images to identify if they are linked to oral submucous fibrosis (OSMF), oral leukoplakia (OLL), oral lichen planus (OLP), or oral squamous cell carcinoma (OSCC). For OSCC, it can also determine how severe the cancer is—welldifferentiated, moderately differentiated, or poorly differentiated—using AI technology. The system predicts the chances of OSMF or OLP/OLL developing into OSCC, giving doctors helpful information about risks. By using genetic markers and digital tools, it provides clear treatment insights and lowers diagnostic costs compared to traditional methods. This invention is set to transform oral cancer detection by making it more affordable and accurate.
In addition to the patent, the research team has recently achieved another significant milestone with their publication in Scientific Data, a high impact factor (9.8) journal from the Nature Publishing Group. Their paper, “High-resolution AI image dataset for diagnosing oral submucous fibrosis and squamous cell carcinoma,” highlights the dataset underpinning their innovation, offering a valuable resource for researchers worldwide.
This accomplishment is shared with distinguished collaborators, including Dr. Akhilanand Chaurasia, Dr. Arpita Rai, Dr. Deepika Mishra, and Dr. Charbel Darido, whose contributions have been pivotal.
Together, these achievements have significant implications for medical treatment, underscoring the transformative potential of AI-driven solutions in digital pathology and oral cancer research, marking a significant leap toward improved diagnostic and prognostic outcomes.
Professor Mohammad Husain, Director of MCARS at JMI, congratulated all who were part of the study and expressed pride in the achievement.
source: http:/www.jmi.ac.in / Jamia Millia Islamia / Home / by Public Relations Office / December 31st, 2024
UK research team makes significant discovery on path to develop vaccine against global viruses
It’s very pleasing to know that a major breakthrough happened in the global biological science research and innovation of a life-saving vaccine has Bihar connection. Dr. Mumtaz Naiyer, a postdoctoral scientist at University of Southampton, UK originally hailing from Kishanganj (Bihar) with his team has made a significant discovery in efforts to develop a vaccine against Zika, dengue and Hepatitis C viruses that affect millions of people around the world. In a study published in Science Immunology, researchers have shown that natural killer cells (NK cells), which are a fundamental part of the body’s immune system, can recognise many different viruses including global pathogens such as Zika, dengue and Hepatitis C viruses, through a single receptor called KIR2DS2.
A native of Thakurganj (Kishanganj), Dr. Mumtaz Naiyer, the first author of the paper, said: “This is a well-presented study and a significant advancement in this field that identifies the important role of the receptor KIR2DS2. Since I come from India, which has thousands of cases of dengue each year, I can understand the suffering of patients with dengue. Nothing would give me greater pleasure than to ease the suffering of these dengue-affected patients.”
The study, which was funded by the Wellcome Trust and the Medical Research Council, analysed DNA from more than 300 patients exposed to the Hepatitis C virus, which showed that the KIR2DS2 receptor was associated with successfully clearing the virus. The team then identified that the immune system targeted the NS3 helicase protein of this using the receptor and found that it prevented the virus multiplying. They went on to demonstrate that this same mechanism could be important for many different viruses for example the Zika and dengue viruses, which also contain a region within their NS3 helicase protein that is recognised by the KIR2DS2 receptor.
The researchers now need to determine whether these KIR2DS2+ NK cells are protective during acute flaviviral infections, and are hoping to develop a vaccine that targets natural killer cells. They believe that a similar process could be used to target cancer.
Lead researcher Salim Khakoo, Professor of Hepatology, said the findings are very exciting and could change the way viruses are targeted by vaccines but warned that the research is still at an early stage, and animal studies/clinical trials will be needed to test the findings.
Professor Khakoo added: “Cancer treatments that use the body’s own immune system are becoming more common. Our findings present a completely new strategy for virus therapeutics which could be easily translated into the field of cancer. The next few years are going to be very exciting in this field.”
Giving back to the community that has supported them for over 30 years was so important to Tasneem and Shafiq Khaleel that they set up an endowed scholarship at MSU Billings in 2006. The Khaleels place a high value on education and where it can take you in life. From the moment Billings, Montana, became their home, they have reached out to the community to share their Indian culture and to offer help to those in need or educate those who would discriminate against them.
Since those early years at MSU Billings, Dr. Tasneem Khaleel has achieved full professor, was chair of the Biological and Physical Sciences department for many years, served as chair of Graduate Studies, and was Dean of the College of Arts and Sciences. Dr. Shafiq Khaleel has built a successful veterinary practice and a rose garden that is the envy of Billings. According to Tasneem, “We both came to this country with an education that has allowed us to be who we are today. If the scholarship allows even one student to achieve his/her goals, it will be one more educated citizen who will have the potential to make a difference.”
The Tasneem and Shafiq Khaleel Endowed Scholarship was designed to help motivated students achieve their goals and ease some of their financial burden in completing their education. The first scholarship was awarded in academic year 2008-2009.
Impact
I am humbled to have been given the opportunity to receive the special scholarship from you both. Dr. Tasneem Khaleel, you have been a role model for me since I had you as my first science class professor at MSUB. I was honored to meet Dr. Shafiq and shake your hand that one afternoon when you picked Dr. Khaleel up from work. The scholarship you both have provided will give me the opportunity to help pay for my college another year at MSUB; it will forever be remembered. Impacting my life to support one more year of school is a stepping stone that will forever support my future endeavors. Again, thank you.” — Sarah G., Biology and Pre-Professional Medicine major
